Next-Generation Sequencing Library Preparation Market Share, Size, Trends, Industry Analysis Report: By Sequencing Type (Targeted Genome Sequencing and Whole Genome Sequencing), By Product, By Application, By End User, and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) – Market Forecast, 2024–2032
- Published Date:Sep-2024
- Pages: 117
- Format: PDF
- Report ID: PM5044
- Base Year: 2023
- Historical Data: 2019-2022
Next-Generation Sequencing Library Preparation Market Overview
The global next-generation sequencing library preparation market size was valued at USD 1,619.26 million in 2023. The market is projected to grow from USD 1,823.94 million in 2024 to USD 4,787.38 million by 2032, exhibiting a CAGR of 12.8% during forecast period.
The next-generation sequencing (NGS) library preparation market focuses on technologies and solutions for preparing biological samples, such as DNA or RNA, for NGS. This crucial step involves converting samples into a format suitable for sequencing, enabling accurate and high-throughput genetic analysis. The market includes tools, reagents, and services essential for genomics research, diagnostics, and personalized medicine.
The industry is rapidly expanding due to advancements in genomic research and the increasing adoption of NGS technologies across various applications, including personalized medicine, cancer research, and drug discovery. Factors such as rising demand for efficient and high-throughput sequencing methods, technological innovations that enhance library preparation processes, and the decreasing costs of sequencing, which make it more accessible, drive the market growth. Emerging trends in the market are the development of automation and high-throughput solutions, integration with bioinformatics tools, and the growing emphasis on personalized and precision medicine. Additionally, the increasing focus on genomics-based diagnostics and therapeutics fuels the demand for sophisticated library preparation techniques.
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Next-Generation Sequencing Library Preparation Market Trends
Increased Adoption of Automation and High-Throughput Solutions
Automation streamlines the library preparation process, reducing manual labor and minimizing errors, which is crucial for high-volume sequencing projects. High-throughput solutions such as advanced robotic systems and automated liquid handling enable labs to process multiple samples simultaneously, significantly increasing efficiency and throughput. This trend is driven by the growing demand for rapid and cost-effective sequencing services, as well as the rising requirement for scalable solutions that can handle the ever-expanding volume of genomic data. The adoption of these technologies is expected to rise as laboratories and research institutions seek to enhance their operational capabilities and deliver faster and reliable results. Owing to all these factors, integration of automation and high-throughput solutions is expected to revolutionize the next-generation sequencing (NGS) library preparation market during the forecast period.
Expansion of Applications in Personalized Medicine and Drug Discovery
The application of NGS library preparation in personalized medicine and drug discovery is expanding, driven by the increasing emphasis on tailoring treatments to individual genetic profiles and the need for novel drug targets. Personalized medicine leverages genomic data to customize patient care, improve treatment efficacy, and reduce adverse effects. NGS library preparation plays a critical role in generating the comprehensive genomic data required for such applications. In drug discovery, NGS facilitates the identification of genetic variations associated with diseases and potential therapeutic targets, accelerating the development of new drugs. This trend would be fueled by advancements in genomic research and the growing recognition of the potential of precision medicine to transform healthcare outcomes.
Technological Innovations Enhancing Library Preparation Processes
Technological innovations are making NGS library preparation processes more efficient and cost-effective. Advances in sequencing chemistries, library preparation kits, and reagents are enabling more accurate and faster generation of sequencing libraries. Innovations such as improved adapters, barcoding techniques, and high-fidelity enzymes are addressing challenges related to library complexity and quality. Additionally, the development of new methods for library enrichment and amplification is advancing the capabilities of NGS. These technological improvements are driven by ongoing research and development efforts aimed at overcoming existing limitations and meeting the evolving needs of the genomics community. Emergence of these technological innovations is expected to drive the growth of the NGS library preparation market in the coming years.
Next-Generation Sequencing Library Preparation Market Segment Insights
Next-Generation Sequencing Library Preparation Market – Sequencing Type Insights
In the global next-generation sequencing (NGS) library preparation market, the segmentation by sequencing type reveals distinct trends and growth dynamics. The whole genome sequencing (WGS) segment dominates the market due to its comprehensive approach, providing a complete view of the entire genome and offering valuable insights into genetic variations and structural anomalies. WGS is widely used in research and clinical applications, including personalized medicine and genetic research, which sustains its leading position. However, the targeted genome sequencing (TGS) is emerging as a rapidly growing segment. TGS focuses on specific regions of interest within the genome, such as genes associated with particular diseases or traits, making it highly efficient and cost-effective for focused studies and clinical diagnostics. The increasing demand for precise, disease-specific information and advancements in targeted sequencing technologies are driving rapid growth of this segment.
The growth of the TGS segment is also supported by its ability to offer more streamlined and affordable solutions than WGS, particularly in areas such as oncology and pharmacogenomics where specific genetic information is critical. As healthcare systems and research institutions increasingly prioritize precision medicine and cost-effective sequencing solutions, the adoption of TGS is accelerating. This shift reflects the broader trend toward more targeted and actionable genomic data, driving significant growth in the TGS segment while maintaining the dominant position of WGS in the market.
Next-Generation Sequencing Library Preparation Market – Product Insights
In the global next-generation sequencing (NGS) library preparation market, the segmental analysis reveals that reagents & consumables segment dominates the market, due to their critical role in the sequencing workflow. Reagents and consumables include a wide range of essential components such as enzymes, buffers, and adapters, which are necessary for preparing sequencing libraries. This segment benefits from the recurring need for these products in ongoing research and clinical applications.
The market for the instruments segment is witnessing a higher growth rate. The instruments include advanced automated systems and high-throughput platforms. The surge in demand for automation to increase efficiency and throughput in sequencing processes is propelling this market growth for the segment. As laboratories and research institutions seek sophisticated and scalable solutions, there is a rising demand for these instruments. It reflects the increasing emphasis on enhancing operational capabilities and handling larger volumes of data.
Next-Generation Sequencing Library Preparation Market – Application Insights
The global next-generation sequencing (NGS) library preparation market, based on application, is segmented into drug & biomarker discovery, disease diagnostics, and others. The drug & biomarker discovery segment dominates the market, driven by the increasing focus on personalized medicine and the need for identifying novel drug targets and biomarkers. This segment benefits from the ability of NGS to provide comprehensive genomic data, which is essential for understanding disease mechanisms and developing targeted therapies. The drug & biomarker discovery, while still dominant, is experiencing more steady growth as it becomes a critical component of drug development pipelines.
The disease diagnostics segment also holds a significant market share as NGS technologies are increasingly used for genetic and genomic testing to diagnose a range of diseases, including cancers and rare genetic disorders. The segment is supported by the growing adoption of genomic diagnostics and advancements in sequencing technologies that enable accurate and faster disease detection. The disease diagnostics is highest growing segment, reflecting the rising demand for precise and timely diagnostic solutions in clinical settings. The increasing prevalence of genetic disorders, advances in NGS technology that enhance sensitivity and accuracy, and the shift toward personalized healthcare drive the next-generation sequencing library preparation market growth for this segment. However, the others segment, which includes various niche applications, contributes a smaller share but is expanding as new use cases for NGS emerge. Overall, the NGS library preparation market is evolving with significant growth in diagnostic applications and steady advances in drug discovery.
Next-Generation Sequencing Library Preparation Market – End User Insights
In the global next-generation Sequencing (NGS) library preparation market, the segmental analysis by end user reveals distinct trends in market dominance and growth. The hospitals and clinics segment dominates the market, driven by the increasing adoption of NGS technologies for diagnostic and clinical applications. The integration of NGS into routine clinical practice for personalized medicine and targeted therapies has fueled substantial demand in this segment. However, the academic and research institutions segment is emerging as the highest-growing segment owing to the expanding research initiatives and grants focusing on genomics and the increasing emphasis on genomic research to drive scientific discovery and innovation. These institutions are leveraging NGS technologies for diverse research applications, including cancer genomics, rare diseases, and evolutionary studies.
The pharmaceutical and biotechnology companies segment also plays a significant role, driven by their need for high-throughput genomic analysis in drug development and biomarker discovery. Their demand for NGS library preparation is fueled by the industry's focus on precision medicine and the need for novel therapeutic targets. The others segment, which includes contract research organizations and government agencies, shows moderate growth, reflecting their specialized needs and contributions to the overall NGS market. The dynamic shifts in these segments highlight the evolving landscape of NGS applications and the growing importance of advanced library preparation technologies across different sectors.
Next-Generation Sequencing Library Preparation Market, Segmental Coverage, 2019 - 2032 (USD million)
Source: Secondary Research, Primary Research, PMR Database and Analyst Review
Next-Generation Sequencing Library Preparation Market Regional Insights
By region, the study provides the market insights into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. In the global next-generation sequencing (NGS) library preparation market, North America is the dominating region owing to its advanced healthcare infrastructure, high research funding, and strong presence of leading biotechnology and pharmaceutical companies. The region benefits from substantial investments in genomics research, a high rate of technological adoption, and a well-established network of academic and clinical institutions driving innovation and demand for NGS technologies. Additionally, North America's supportive regulatory environment and extensive healthcare networks facilitate the rapid integration and application of NGS in clinical and research settings, further solidifying its leadership position in the global market.
The NGS library preparation market in Europe is characterized by a strong emphasis on research and development, driven by robust funding from public and private sectors. European countries, particularly Germany, the UK, and France, are prominent players, with significant investments in genomic research and healthcare innovation. The region benefits from a well-established network of academic institutions and research centers, fostering collaborations and advancements in NGS technologies. Additionally, rising focus on personalized medicine and genetic research in the region, supported by the European Union’s Horizon Europe program, contributes to the regional market growth. However, the market growth in Europe is somewhat constrained by diverse regulatory frameworks and varying levels of technology adoption across different countries.
Next-Generation Sequencing Library Preparation Market, Regional Coverage, 2019 - 2032 (USD million)
Source: Secondary Research, Primary Research, PMR Database and Analyst Review
The Asia Pacific NGS library preparation market is experiencing rapid growth, driven by increasing investments in genomics research, rising healthcare expenditures, and a growing focus on personalized medicine. Countries such as China and India are emerging as significant players, with substantial government and private sector funding supporting advancements in NGS technologies. The expanding biotechnology and pharmaceutical industries, coupled with the rising prevalence of genetic disorders and cancer, fuel the demand for NGS solutions. Additionally, the region’s large and diverse population presents a unique opportunity for NGS applications in clinical diagnostics and research. The market in Asia Pacific is expected to grow in the coming years due to ongoing investments in healthcare infrastructure and increasing awareness of genomic technologies.
Next-Generation Sequencing Library Preparation Market – Key Players and Competitive Insights
Illumina, Thermo Fisher Scientific, and Agilent Technologies are a few of the key players in the global next-generation sequencing (NGS) library preparation market. The players are recognized for their comprehensive NGS solutions and advanced library preparation kits. Other notable companies are Roche, QIAGEN, and Bio-Rad Laboratories, offering a range of products and services that cater to diverse genomic research needs. Additional significant players include Beckman Coulter, Pacific Biosciences, and Oxford Nanopore Technologies, known for their innovative technologies and specialized solutions. Also, a few companies contributing to the market are Hamilton Company, Fluidigm Corporation, and 10x Genomics, which provide automation and high-throughput capabilities. Companies such as Genomatix Software, Dovetail Genomics, and Array Technologies contribute unique technologies and advancements to the NGS library preparation.
In terms of competitive analysis, Illumina and Thermo Fisher Scientific dominate the market due to their extensive product portfolios, strong R&D capabilities, and global reach. Illumina’s leadership is supported by its broad range of NGS platforms and library preparation kits that cater to various research and clinical applications. Thermo Fisher Scientific’s competitive edge lies in its comprehensive offerings and integration of NGS technologies with other laboratory services. Agilent Technologies and Roche are also key players, leveraging their extensive experience in molecular biology and genomic research to drive innovation and market presence.
The next-generation sequencing library preparation market is characterized by intense competition among key players, driven by continuous technological advancements and a push for cost-effective solutions. Companies are increasingly focusing on developing automated and high-throughput library preparation systems to enhance efficiency and reduce errors. Additionally, there is an emerging trend toward integrating NGS library preparation with advanced bioinformatics tools to streamline data analysis and interpretation. As the market evolves, companies are investing in strategic partnerships and acquisitions to expand their capabilities and market reach, ensuring they remain competitive in the rapidly growing NGS landscape.
Illumina is a major player in the global next-generation sequencing (NGS) library preparation market, renowned for its comprehensive range of NGS solutions and advanced library preparation kits. Illumina’s dominance is underscored by its cutting-edge sequencing platforms, including the NovaSeq and NextSeq systems, which offer high-throughput and accurate sequencing capabilities. The company's strong R&D focus and extensive product portfolio cater to various research and clinical applications, solidifying its market leadership.
Thermo Fisher Scientific is another major player, known for its extensive range of NGS library preparation products and integration of sequencing technologies with other laboratory services. Thermo Fisher’s portfolio includes the Ion Proton and Ion GeneStudio platforms, which offer high-speed and cost-effective sequencing solutions. The company's competitive edge lies in its broad product offerings and global presence, which support diverse applications in genomics and molecular biology.
Key Companies in Next-Generation Sequencing Library Preparation Market
- Illumina
- Thermo Fisher Scientific
- Agilent Technologies
- Roche
- QIAGEN
- Bio-Rad Laboratories
- Beckman Coulter
- Pacific Biosciences
- Oxford Nanopore Technologies
- Hamilton Company
- Fluidigm Corporation
- 10x Genomics
- Genomatix Software
- Dovetail Genomics
- Array Technologies
Next-Generation Sequencing Library Preparation Industry Developments
- In June 2024, Thermo Fisher launched a new Ion GeneStudio S5 System, designed to provide accessible and efficient sequencing capabilities for a range of applications from basic research to clinical diagnostics.
- In September 2023, Illumina acquired GRAIL, a company specializing in early cancer detection. The acquisition aims to enhance Illumina’s capabilities in personalized medicine and genomic-based diagnostics.
Next-Generation Sequencing Library Preparation Market Segmentation
Next-Generation Sequencing Library Preparation Market – Sequencing Type Outlook
- Targeted Genome Sequencing
- Whole Genome Sequencing
Next-Generation Sequencing Library Preparation Market – Product Outlook
- Reagents & Consumables
- Instruments
Next-Generation Sequencing Library Preparation Market – Application Outlook
- Drug & Biomarker Discovery
- Disease Diagnostics
- Others
Next-Generation Sequencing Library Preparation Market – End User Outlook
- Hospitals and Clinics
- Academic and Research Institutions
- Pharmaceutical and Biotechnology Companies
- Others
Next-Generation Sequencing Library Preparation Market – Regional Outlook
- North America
- US
- Canada
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Netherlands
- Russia
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Malaysia
- South Korea
- Indonesia
- Australia
- Vietnam
- Rest of Asia Pacific
- Middle East & Africa
- Saudi Arabia
- UAE
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Mexico
- Brazil
- Argentina
- Rest of Latin America
Next-Generation Sequencing Library Preparation Market Report Scope
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Report Attributes |
Details |
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Market size value in 2023 |
USD 1,619.26 million |
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Market size value in 2024 |
USD 1,823.94 million |
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Revenue forecast in 2032 |
USD 4,787.38 million |
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CAGR |
12.8% from 2024 to 2032 |
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Base year |
2023 |
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Historical data |
2019–2022 |
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Forecast period |
2024–2032 |
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Quantitative units |
Revenue in USD million and CAGR from 2024 to 2032 |
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Report coverage |
Revenue Forecast, Market Competitive Landscape, Growth Factors, and Trends |
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Segments covered |
|
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Regional scope |
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|
Competitive landscape |
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Report format |
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Customization |
Report customization as per your requirements with respect to countries, region, and segmentation. |
How the report is valuable for an organization?
Workflow/Innovation Strategy: The next-generation sequencing library preparation market has been segmented on the basis of sequencing types, products, applications, and end users. Moreover, the study provides the reader with a detailed understanding of the different segments at global and regional level.
Growth/Marketing Strategy: To drive growth in the global next-generation sequencing (NGS) library preparation market, companies are focusing on several key strategies. These include expanding their product portfolios with innovative and high-throughput solutions to meet diverse research needs and enhancing automation capabilities to increase efficiency. Strategic partnerships and acquisitions are being leveraged to access new technologies and markets, while investments in R&D ensure the development of cutting-edge products. Additionally, companies are targeting emerging markets with tailored solutions and engaging in aggressive marketing campaigns to raise awareness and adoption of their NGS technologies. Building strong relationships with key research institutions and healthcare providers also plays a crucial role in their business growth.
FAQ's
The global next generation sequencing library preparation market size was valued at USD 1,619.26 million in 2023 and is projected to grow to USD 4,787.38 million by 2032.
The global market is projected to register a CAGR of 12.8% during 2023–2032.
In the global next-generation sequencing (NGS) library preparation market, North America is the dominating region owing to its advanced healthcare infrastructure, high research funding, and strong presence of leading biotechnology and pharmaceutical companies.
Illumina, Thermo Fisher Scientific, and Agilent Technologies are among the key players in the global next-generation sequencing (NGS) library preparation market. The companies are recognized for their comprehensive NGS solutions and advanced library preparation kits.
The whole genome sequencing segment dominated the market in 2023.
The consumables segment accounted for a larger market share.
The global next-generation sequencing (NGS) library preparation market focuses on the development, production, and sale of products and services used to prepare DNA or RNA samples for sequencing on NGS platforms. Library preparation is a critical step in the NGS workflow, involving the fragmentation, amplification, and addition of adapters to nucleic acid samples to create libraries that are compatible with sequencing machines. This market encompasses a range of reagents, kits, and automation solutions designed to enhance the efficiency, accuracy, and throughput of NGS processes. The market is driven by the increasing adoption of NGS technologies in various fields such as clinical diagnostics, genomics research, personalized medicine, and drug discovery, as well as continuous advancements in sequencing technologies and decreasing costs of sequencing.
A few key trends in the global next-generation sequencing (NGS) library preparation market are described below: Increased Adoption of Automation: Growing integration of automated and high-throughput solutions to enhance efficiency and reduce errors in library preparation processes. Expansion of Personalized Medicine: Rising use of NGS in personalized medicine and precision medicine, driving demand for sophisticated library preparation techniques. Technological Innovations: Continuous advancements in sequencing chemistries, library preparation kits, and reagents, improving accuracy and efficiency. Cost Reduction: Decreasing costs of sequencing make NGS technologies more accessible and drive market growth.
A new company entering the global next-generation sequencing (NGS) library preparation market must focus on developing innovative, high-throughput, and automated solutions to enhance efficiency and accuracy in sample preparation. Investing in R&D to create cutting-edge, cost-effective products tailored to emerging applications such as personalized medicine and cancer genomics can provide a competitive edge. Building strategic partnerships with leading research institutions and healthcare providers can facilitate market entry and growth. Additionally, integrating advanced bioinformatics tools for seamless data analysis and offering robust customer support and training services can help differentiate the company and attract a loyal customer base.
Companies manufacturing and distributing next-generation sequencing library preparation products, kits, and other consumables and other consulting firms must buy the report
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