Lipid Nanoparticle Raw Materials Market size was valued at USD 211.19 million in 2023. The market is anticipated to grow from USD 221.70 million in 2024 to USD 333.85 million by 2032, exhibiting the CAGR of 5.2% during the forecast period.
Lipid nanoparticles are receiving an increase in demand with the growing their application in drug development activities. This is due to its enormous potential to deliver the required medicines to the targeted area, leading to optimal functioning in the disease recovery processes. Thus, the demand for raw materials that develop lipid nanoparticles, such as lipids, surfactants, polymers, and stabilizers is anticipated to register significant demand in the next few years. Furthermore, the rising research studies exploring lipid nanoparticles are likely to drive the lipid nanoparticle raw materials market expansion in the long run.
Additionally, the increasing prevalence of generative medicine use in the healthcare industry is rising the use of lipid nanoparticles. They play an effective role in tissue engineering processes as they require delivery agents. Moreover, the growing measures to enhance their product line are likely to bolster the lipid raw materials demand in the next few years. For instance, in June 2023, Bayer AG entered into a collaboration framework with Acuitas Therapeutics, Inc. to expand its gene therapy product offering with lipid nanoparticle technology.
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However, the presence of superior substitutes, such as exosomes, liposomes, and dendrimers, and the higher manufacturing costs are expected to restrict the use of lipid nanoparticles and in turn, the raw materials that produce lipid nanoparticles in the global market.
Rising incidence of lung diseases
The growing number of people suffering from lung diseases is fueling pharmaceutical studies exploring the development of new drugs for treatment. A 2023 study announced the innovation of nanoparticles that can execute gene editing in cystic fibrosis and lung diseases. As per the National Institutes of Health, around 45% of the deaths are due to fibrotic disorders in the United States. This will further boost the production of new nanoparticles and significantly support the demand for raw materials.
Increasing adoption of mRNA technology in multiple therapeutic formulations
The mRNA technology altered the way people create new therapeutics in the global marketplace. It is widely employed in the formulation of the COVID-19 vaccine due to its superior delivery system. The ongoing innovations in pharmaceutical and biotechnology companies are creating new growth opportunities for the lipid nanoparticle raw materials. For instance, in March 2023, researchers developed the new lipid nanoparticle-based CRISPER carrier system.
Furthermore, rising awareness about the importance of lipid nanoparticles in delivering RNA to the required cells is driving the use of them in vaccination formulations. A 2023 study published in Nature Biomedical Engineering focused on promoting the immunogenicity of lipid nanoparticle-based mRNA vaccines by engineering COVID-19 antigens and nanoparticles. Researchers unveiled the potential to develop intranasal-based vaccine administration for respiratory and COVID-19 diseases with this method.
Complex production process is likely to impede market growth
The complexities associated with the production of lipid nanoparticles are a major challenging factor restricting the lipid nanoparticle raw materials, as it consequently lowers the demand for raw materials in the study period. The ineffectiveness of delivering the molecules to the prescribed area due to their intrinsic instability is likely to limit their adoption, driven by the importance of a stable carrier system in vaccine development.
The market is primarily segmented based on product, disease indication, application, end-use, and region.
By Product |
By Disease Indication |
By Application |
By Region |
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Kits segment is expected to witness the highest growth during the forecast period
The kits segment will grow rapidly, mainly driven by its compatibility with the vaccine and gene therapy development processes. Lipid nanoparticles in the form of kits give flexibility to researchers and offer customization facilities in the pharmaceutical industry. The affordability of ionizable lipids in the form of kits is anticipated to drive growth in the coming years. Moreover, the increasing innovations by market players are propelling market expansion. For instance, in March 2024, CordenPharma unveiled the new lipid nanoparticle starter kits to produce mRNA therapies.
Therapeutics segment held the significant market revenue share in 2023
The therapeutics segment held a significant market share in revenue in 2023. The growth of the lipid nanoparticle raw materials is highly influenced by the increasing drug innovation. For instance, in October 2023, BIOVECTRA entered into a service agreement with Acuitas Therapeutics for the delivery of distinct lipid nanoparticles to produce mRNA-based therapeutics.
Additionally, the increasing research and development focusing on evaluating the application of lipid nanoparticles in several therepeutic formulations is anticipated to drive significant demand for lipid nanoparticle raw materials. For instance, a 2023 study revealed the use of mRNA and lipid nanoparticles for the treatment of blindness.
Pharmaceutical & biotechnology companies segment expected to witness significant growth over the study timeframe
The pharmaceutical & biotechnology companies segment anticipated to register significant growth during the forecast period. The rising investments in evaluating the lipid nanoparticle capability in handling medicine are showcasing dynamic opportunities for the lipid nanoparticle raw materials market. For instance, in April 2023, Sanofi announced the grant of USD 25 million to Daniel Anderson’s MIT professor lab to assist in the development of RNA therapies and vaccines.
North America region registered the largest share of the global market in 2023
The North America region held the dominant market share in 2023. This is due to the existence of prominent pharmaceutical and biotechnological companies investing significant amounts in drug discovery procedures. For instance, in May 2023, Aphios Corporation received the National Institute of Health grant, Phase I Small Business Innovation Research (SBIR), for the development of COVID-19 mRNA vaccines from the United States. These are further boosting the demand for lipid nanoparticle raw materials.
The Asia Pacific region will grow with rapid pace. The significant rise in the prevalence of blood diseases in the region is positively affecting the growth of lipid nanoparticles and, thereby, the raw materials that are used in the production activities. According to the Shalby Hospital, approximately 70,000 people are expected to die annually due to blood cancer, which is the third highest after the United States and China. As more people get affected by blood cancer, there will be a need for treatment medications, including lipid nanoparticles, driven by their capabilities to release the chemical to the targeted area.
Strategic collaborations to drive the competition
The lipid nanoparticle raw materials market is fragmented. The increasing need for lipid nanoparticles is driving the company's initiatives to improve its capacity in the marketplace. Major players are stepping forward with partnerships, collaborations, and acquisitions. For instance, in July 2023, McGill University and Moderna announced the expansion of their collaboration on the latest projects in lipid nanoparticle research.
Some of the major players operating in the global market include:
The lipid nanoparticle raw materials market report emphasizes on key regions across the globe to provide better understanding of the product to the users. Also, the report provides market insights into recent developments, trends and analyzes the technologies that are gaining traction around the globe. Furthermore, the report covers in-depth qualitative analysis pertaining to various paradigm shifts associated with the transformation of these solutions.
The report provides detailed analysis of the market while focusing on various key aspects such as competitive analysis, product, disease indication, application, end-use, and their futuristic growth opportunities.
Report Attributes |
Details |
Market size value in 2024 |
USD 221.70 million |
Revenue forecast in 2032 |
USD 333.85 million |
CAGR |
5.2% from 2024 – 2032 |
Base year |
2023 |
Historical data |
2019 – 2022 |
Forecast period |
2024 – 2032 |
Quantitative units |
Revenue in USD million and CAGR from 2024 to 2032 |
Segments covered |
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Regional scope |
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Competitive Landscape |
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Report Format |
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Customization |
Report customization as per your requirements with respect to countries, region and segmentation. |
The Lipid Nanoparticle Raw Materials Market report covering key segments are product, disease indication, application, end-use, and region.
Lipid Nanoparticle Raw Materials Market Size Worth $333.85 Million By 2032
Lipid Nanoparticle Raw Materials Market exhibiting the CAGR of 5.2% during the forecast period.
North America is leading the global market
key driving factors in Lipid Nanoparticle Raw Materials Market are Rising incidence of lung diseases