Biguanides Market Share, Size, Trends, Industry Analysis Report, By Type (Metformin, Phenformin, Others); By Distribution Channel; By Region; Segment Forecast, 2024- 2032
- Published Date:Jan-2024
- Pages: 116
- Format: PDF
- Report ID: PM4410
- Base Year: 2023
- Historical Data: 2019 – 2022
Report Outlook
- Biguanides Market size was valued at USD 4.96 billion in 2023.
- The market is anticipated to grow from USD 5.08 billion in 2024 to USD 6.19 billion by 2032, exhibiting a CAGR of 2.5% during the forecast period.
Market Introduction
The pivotal driver behind the biguanides market share is their clinical effectiveness, prominently demonstrated by metformin. Renowned for robust efficacy in reducing blood glucose levels among individuals with type 2 diabetes, biguanides operate by curbing hepatic glucose production and enhancing peripheral insulin sensitivity. This dual action contributes significantly to superior glycemic control. With a well-established safety profile, biguanides, led by metformin, emerge as a preferred choice in diabetes management. Healthcare providers prioritize these medications for their tangible and consistent clinical benefits, shaping prescribing practices and fostering continual global demand for biguanides within the antidiabetic market.
In addition, companies operating in the market are concentrating on developing new solutions to cater to the growing market demand.
- For instance, in August 2023, Dr. Reddy’s Laboratories introduced Saxagliptin and Metformin Hydrochloride Extended-Release Tablets in the U.S., presenting its generic alternative to AstraZeneca’s antidiabetic medication Kombiglyze XR. The product's release follows approval from the U.S. Food and Drug Administration.
Affordability is a key driver in the biguanides market size, notably embodied by metformin. Recognized for its cost-effectiveness, metformin's affordability broadens its accessibility across diverse demographics. In a healthcare landscape where cost considerations are paramount, the economic viability of biguanides, particularly metformin, influences prescribing decisions and promotes patient adherence to diabetes management. This affordability factor positions biguanides as an inclusive and practical solution, ensuring that individuals from various socioeconomic backgrounds can access effective diabetes treatment. Consequently, the affordability of metformin plays a pivotal role in sustaining the growth and prominence of the biguanides market share within the domain of antidiabetic therapies.
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Clinical guidelines and recommendations are instrumental drivers propelling the biguanides market industry forecast. These guidelines, consistently endorsing biguanides as a primary treatment for type 2 diabetes, wield significant influence over healthcare practitioners' prescribing patterns. As trusted sources of medical best practices, these guidelines highlight the clinical efficacy and safety profile of biguanides, particularly metformin, positioning them as a preferred initial therapy. The alignment with established recommendations strengthens the confidence of healthcare providers in prescribing biguanides, fostering widespread adoption. This endorsement not only reinforces their pivotal role in diabetes management but also contributes to the sustained growth and prominence of the market, as adherence to established guidelines continues to guide treatment decisions on a global scale.
Industry Growth Drivers
First-Line Treatment is projected to spur the product demand
The recognition of biguanides, especially metformin, as a first-line treatment for type 2 diabetes significantly propels the biguanides market analysis report. Consistent recommendations by medical guidelines underscore their clinical efficacy and well-established safety, making them the preferred initial therapeutic choice worldwide. This status positions biguanides at the forefront of diabetes management, influencing prescribing patterns globally. The emphasis on first-line treatment highlights their crucial role in initiating early and effective diabetes care, contributing to widespread utilization and sustained market demand.
Surging prevalence of type 2 diabetes is expected to drive market growth
The surging prevalence of type 2 diabetes is driving the market. With the global rise in diabetes cases attributed to lifestyle changes and obesity, the demand for effective antidiabetic medications, particularly metformin, is escalating. Biguanides' clinical efficacy in regulating blood glucose levels positions them as a preferred first-line treatment. This prevalence of type 2 diabetes acts as a fundamental catalyst, underscoring the pivotal role of biguanides in addressing the urgent need for comprehensive diabetes management on a widespread scale, influencing their prominence and sustained growth in the market.
Industry Challenges
Prevalence of side effects is likely to impede the market growth
The prevalence of side effects poses a notable constraint on the market. Gastrointestinal side effects, including nausea and diarrhea, are common with medications like metformin, impacting patient compliance and treatment persistence. Concerns about these adverse reactions may discourage healthcare providers from prescribing biguanides, especially in individuals with a history of intolerance. Patient discomfort and dissatisfaction may lead to a reluctance to initiate or continue treatment, influencing the overall market demand for biguanide medications.
Report Segmentation
The market analysis is primarily segmented based on type, distribution channel, and region.
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By Type |
By Distribution Channel |
By Region |
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By Type Analysis
Metformin segment accounted for significant market share in 2023
The metformin segment accounted for a significant market share in 2023. Metformin, a key biguanide for type 2 diabetes, excels in glycemic control by reducing hepatic glucose production and enhancing insulin sensitivity. Its proven safety profile minimizes hypoglycemia risk, providing a reliable, long-term solution. Metformin's potential cardiovascular benefits enhance its appeal for those with diabetes and cardiovascular risk. Notably, weight-neutral or promoting modest weight loss, it offers a holistic approach to diabetes management.
By Distribution Channel Analysis
Retail pharmacy segment held significant market revenue share in 2023
The retail pharmacy segment held a significant revenue share in 2023. Biguanides, like metformin, are readily available through retail pharmacies, providing convenient access for patients with prescriptions. Retail outlets serve as accessible points for individuals to obtain and fill their prescribed biguanides. Pharmacists play a crucial role in offering guidance on proper usage and addressing queries. This retail distribution channel ensures the widespread availability and accessibility of biguanides, contributing to effective management, particularly for conditions like type 2 diabetes.
Regional Insights
North America region accounted significant market share in 2023
In 2023, the North American region accounted for a significant market share. The North American biguanides market share is dynamic, driven by the pivotal role of medications like metformin in managing type 2 diabetes. A diverse array of pharmaceutical companies operates in this region, continually innovating formulations for enhanced efficacy and patient adherence. Regulatory standards, particularly those set by the U.S. FDA, influence market dynamics, ensuring the quality and safety of biguanide products. With diabetes prevalence on the rise, heightened healthcare awareness, and strategic industry collaborations, the North American market remains competitive and poised for growth, addressing the evolving needs of diabetes management in the region.
Over the projected period, the Asia-Pacific region is likely to experience significant growth. Asian countries experiencing a rising prevalence of diabetes witness a growing demand for these medications. Local pharmaceutical companies contribute to the market with diverse formulations, adapting to regional preferences and regulatory frameworks. Government initiatives and healthcare policies in various Asian nations influence access to biguanides.
Key Market Players & Competitive Insights
The landscape of the market is characterized by variety, and the anticipated influx of several new players is poised to intensify competition. Well-established market frontrunners continuously upgrade their technologies to uphold a competitive edge, emphasizing efficiency, integrity, and safety. These entities give precedence to strategic initiatives including partnerships, enhancements to products, and collaborative ventures, aiming to outperform their peers. Their objective is to secure a significant biguanides market share.
Some of the major players operating in the global market include:
- AstraZeneca
- Bayer AG
- Boehringer Ingelheim
- Bristol Myers Squibb
- Dr. Reddy's Laboratories
- Eli Lilly and Company
- GlaxoSmithKline
- Lupin Pharmaceuticals, Inc.
- Merck & Co., Inc.
- Novartis
- Pfizer Inc.
- Sanofi
- Sun Pharmaceutical Industries Ltd.
- Teva Pharmaceutical Industries Ltd.
- Zydus Cadila
Recent Developments
- In February 2023, Zydus Pharmaceuticals Inc. secured provisional approval from the United States Food and Drug Administration (USFDA) for Canagliflozin and Metformin Hydrochloride Tablets.
- In August 2023, Akums Drugs and Pharmaceuticals introduced a remedy in the battle against diabetes - Vildagliptin SR and Metformin SR tablets. Tailored for individuals managing type 2 diabetes mellitus with insufficient control using metformin alone, this combination assures proficient glycemic regulation.
Report Coverage
The market report emphasizes on key regions across the globe to provide better understanding of the product to the users. Also, the report provides market insights into recent developments, trends and analyzes the technologies that are gaining traction around the globe. Furthermore, the report covers in-depth qualitative analysis pertaining to various paradigm shifts associated with the transformation of these solutions.
The report provides detailed analysis of the market while focusing on various key aspects such as competitive analysis, types, distribution channels and their futuristic growth opportunities.
Biguanides Market Report Scope
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Report Attributes |
Details |
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Market size value in 2024 |
USD 5.08 billion |
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Revenue forecast in 2032 |
USD 6.19 billion |
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CAGR |
2.5% from 2024 – 2032 |
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Base year |
2023 |
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Historical data |
2019 – 2022 |
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Forecast period |
2024 – 2032 |
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Quantitative units |
Revenue in USD billion and CAGR from 2024 to 2032 |
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Segments covered |
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Regional scope |
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Competitive Landscape |
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Report Format |
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Customization |
Report customization as per your requirements with respect to countries, region and segmentation. |
FAQ's
The Biguanides Market report covering key segments are type, distribution channel, and region.
Biguanides Market Size Worth $6.19 Billion By 2032
Biguanides Market exhibiting the CAGR of 2.5% during the forecast period.
North American is leading the global market
key driving factors in Biguanides Market First-Line Treatment is projected to spur the product demand
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